Owner Direct Vacation
Rentals in Mayo
The Best Owner Direct Vacation Rentals in Mayo. Explore thousands of vacation home rentals, large cabins, and villas near Mayo
GUESTS
Explore the Best Mayo Vacation Homes
Looking for the perfect place to stay in Mayo? Discover a curated collection of vacation rentals offering comfort, convenience, and authentic Mayo character. Whether you want a beachfront condo, a cozy family home, or a pet-friendly stay close to downtown, Owner Direct makes it easy to compare verified options for your next trip.
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- luxury villas
- beachfront homes
- pet-friendly rentals
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Why Travelers Love Using
Owner Direct to
Find Mayo Vacation Rentals
What makes our vacation homes stand out?

Verified Properties
Every vacation home shown on Owner Direct comes from trusted travel sources and verified hosts, so you can browse with confidence.

Value You Can Trust
Compare a range of properties and find fair, transparent pricing—no hidden fees.

Endless Variety
From oceanfront condos and coastal cottages to luxury villas and family homes, there's a rental to fit every traveler and budget.
More Places to Stay Near Mayo
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Popular Neighborhoods for Mayo Vacation Rentals
What are the best areas to stay in Mayo
Discover the top neighborhoods in Mayo and choose a place that suits your stay.
Lafayette Blue Springs State Park
Lafayette Blue Springs State Park VACATION RENTALSAlton
Alton VACATION RENTALSLafayette County
Lafayette County VACATION RENTALSWednesday Jan 28
Mayo, Florida







Common Vacation Rental Amenities Typical Vacation Rental Amenities
What sort of amenities will be available at your stay?
Our Mayo vacation rentals are designed for comfort and convenience, with everything you need for a relaxing stay.
Indoor Amenities
Fully equipped kitchens
Spacious living areas with streaming TVs
Complimentary Wi-Fi
Air conditioning and heating
In-unit washer and dryer
Plush bedding and comfortable furniture
Outdoor Amenities
Balconies or patios with coastal views
Private or shared pools
BBQ grills and outdoor dining areas
On-site parking
Easy access to beaches and attractions
More Vacation Rentals You May Like Near Mayo
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How to Reserve Your Mayo Vacation Rental
Booking Made Simple
Owner Direct helps travelers find verified vacation rentals from trusted sources. Once you select a property you love, you’ll be guided to our partner’s secure booking platform to complete your reservation.
SEARCH PROPERTIES
Use filters for location, amenities, and budget.
VIEW DETAILS
Check photos, reviews, and features for your top picks.
BOOK SECURELY
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Mayo Vacation Rental FAQs
1. What are the top vacation rentals in Mayo?
There are a lot of options in Mayo. If you plan on staying in the Mayo area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Mayo:
- Red Bird Cabin-Peace & Quiet Near the Suwannee River
- Suwannee River Retreat with Private Dock, Free Kayaks, and Fire pit
- Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
- RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house
- The Chalet On the Suwannee River
- Lake View Country Glamping on 40+ Serene Acres
- The Best memories are made on the Suwannee River
- 15 ACRE RIVER FRONT CABIN HOUSE ON THE SUWANNEE, WITH SPRING WALKING DISTANCE
- Friendlys River Retreat private nRustic Camping Cabin sleeps 4+with tent camping
- Cindys Motel
2. Which vacation homes in Mayo are best for families?
If you are looking for a family-friendly vacation home in Mayo, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Mayo:
3. How many vacation rentals are available in Mayo?
Currently, the total number of properties listed in 2026 is over 45 in the Mayo area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Mayo.