Owner Direct Vacation
Rentals in Seneca
The Best Owner Direct Vacation Rentals in Seneca. Explore thousands of vacation home rentals, large cabins, and villas near Seneca
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Explore the Best Seneca Vacation Homes
Looking for the perfect place to stay in Seneca? Discover a curated collection of vacation rentals offering comfort, convenience, and authentic Seneca character. Whether you want a beachfront condo, a cozy family home, or a pet-friendly stay close to downtown, Owner Direct makes it easy to compare verified options for your next trip.
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What makes our vacation homes stand out?

Verified Properties
Every vacation home shown on Owner Direct comes from trusted travel sources and verified hosts, so you can browse with confidence.

Value You Can Trust
Compare a range of properties and find fair, transparent pricing—no hidden fees.

Endless Variety
From oceanfront condos and coastal cottages to luxury villas and family homes, there's a rental to fit every traveler and budget.
More Places to Stay Near Seneca
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Popular Neighborhoods for Seneca Vacation Rentals
What are the best areas to stay in Seneca
Discover the top neighborhoods in Seneca and choose a place that suits your stay.
Pine Ridge Point
Pine Ridge Point VACATION RENTALSEmerald Pointe
Emerald Pointe VACATION RENTALSSaxony Forest
Saxony Forest VACATION RENTALSMoorings of Keowee
Moorings of Keowee VACATION RENTALSIndian Oaks
Indian Oaks VACATION RENTALSSerenity Bay
Serenity Bay VACATION RENTALSShelter Cove
Shelter Cove VACATION RENTALSNormandy Shores
Normandy Shores VACATION RENTALSNorthlake Estates
Northlake Estates VACATION RENTALSKeowee
Keowee VACATION RENTALSSaturday Jan 31
Seneca, South Carolina







Common Vacation Rental Amenities Typical Vacation Rental Amenities
What sort of amenities will be available at your stay?
Our Seneca vacation rentals are designed for comfort and convenience, with everything you need for a relaxing stay.
Indoor Amenities
Fully equipped kitchens
Spacious living areas with streaming TVs
Complimentary Wi-Fi
Air conditioning and heating
In-unit washer and dryer
Plush bedding and comfortable furniture
Outdoor Amenities
Balconies or patios with coastal views
Private or shared pools
BBQ grills and outdoor dining areas
On-site parking
Easy access to beaches and attractions
More Vacation Rentals You May Like Near Seneca
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How to Reserve Your Seneca Vacation Rental
Booking Made Simple
Owner Direct helps travelers find verified vacation rentals from trusted sources. Once you select a property you love, you’ll be guided to our partner’s secure booking platform to complete your reservation.
SEARCH PROPERTIES
Use filters for location, amenities, and budget.
VIEW DETAILS
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BOOK SECURELY
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Seneca Vacation Rental FAQs
1. What are the top vacation rentals in Seneca?
There are a lot of options in Seneca. If you plan on staying in the Seneca area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Seneca:
- 😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks
- Lake Front, Quiet, Private cove on 4.75 acres, Canoe, 2 Kayak, 2 boat docks
- Serenity Bay, Keowee Lakefront Cabin, Covered Dock, Kayaks, Clean, Near Clemson
- 😎 Spacious Lake Hartwell home with cozy cabin appeal, 15 mins to Clemson🐯 WiFi
- Easy access lake front W/beach and boat ramp, waterfront patio, screened porch
- Beautiful waterfront home on a private cove in Lake Keowee w/hot tub
- Spectacular lake home with dock and fire pit- room for all - good pets ok-
- Secluded Seneca/Clemson Lake Hartwell Waterfront, 3 miles to CU
- Pristine views from Lakefront Home
- 20 Minutes to Clemson - Remodeled 4 BR/3 BA Waterfront
2. How many vacation rentals have private pools in Seneca?
There are 6 vacation rentals with private pools near Seneca. Top-rated homes that have access to a swimming pool include:
3. Which vacation homes in Seneca are best for families?
If you are looking for a family-friendly vacation home in Seneca, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Seneca:
4. How many vacation rentals are available in Seneca?
Currently, the total number of properties listed in 2026 is over 457 in the Seneca area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Seneca.